1639220-15-7

1639220-15-7 structure

1639220-15-7 structure

Name: Sigma-1 receptor antagonist 2
Chemical Name: Sigma-1 receptor antagonist 2
CAS Number: 1639220-15-7
Molecular Formula: C₂₀H₂₆ClN₃O₂
Molecular Weight: 375.89
Create Date: 2019-12-08 19:00:19
Modify Date: 2024-01-18 21:21:00
Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1].

Name	Sigma-1 receptor antagonist 2

Description	Sigma-1 receptor antagonist 2 is a potent and selective sigma 1 receptor (σ1 R) antagonist with Kis of 3.88 and 1288 nM for σ1 and σ2 receptor, respectively[1].
Target	Ki: 3.88 nM (σ1 receptor), 1288 nM (σ2 receptor)[1]
References	[1]. Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.

Molecular Formula	C₂₀H₂₆ClN₃O₂
Molecular Weight	375.89