1384082-96-5
1384082-96-5 structure
- Name: (1α,1'S,4β)-Lanabecestat
- Chemical Name: (1α,1'S,4β)-Lanabecestat
- CAS Number: 1384082-96-5
- Molecular Formula: C26H28N4O
- Molecular Weight: 412.53
- Catalog: Signaling Pathways Neuronal Signaling Beta-secretase
- Create Date: 2019-12-08 11:53:19
- Modify Date: 2024-01-10 18:33:41
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(1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1].
| Name | (1α,1'S,4β)-Lanabecestat |
|---|
| Description | (1α,1'S,4β)-Lanabecestat ((1α,1'S,4β)-AZD3293) is a Beta site APP Cleaving Enzymel (BACE1) inhibitor extracted from patent WO2012087237A1, compound 20a, has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively[1]. |
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| Related Catalog | |
| References |
[1]. Gabor Csjernyik, et al. Compounds and their use as bace inhibitors. WO2012087237A1. |
| Molecular Formula | C26H28N4O |
|---|---|
| Molecular Weight | 412.53 |