5853-21-4

5853-21-4 structure

Name: Carpaine hydrochloride
Chemical Name: Carpaine hydrochloride
CAS Number: 5853-21-4
Molecular Formula: C₂₈H₅₁ClN₂O₄
Molecular Weight: 515.17
Create Date: 2019-12-08 13:57:32
Modify Date: 2024-01-22 20:04:47
Carpaine hydrochloride is an alkaloid isolated from Carica papaya Linn anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity[1]. Carpaine hydrochloride has anti-plasmodial activity to prevent malaria[2].

Name	Carpaine hydrochloride

Description	Carpaine hydrochloride is an alkaloid isolated from Carica papaya Linn anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity[1]. Carpaine hydrochloride has anti-plasmodial activity to prevent malaria[2].
In Vivo	Carpaine hydrochloride affects the myocardium directly, it reduces cardiac output, stroke volume, stroke work, and cardiac power in rat, which has been studied for its cardiovascular effects[3].
References	[1]. Zunjar V, et al. Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats. J Ethnopharmacol. 2016 Apr 2;181:20-5. [2]. Julianti T, et al. Quantification of the antiplasmodial alkaloid carpaine in papaya (Carica papaya) leaves. Planta Med. 2014 Aug;80(13):1138-42. [3]. Hornick CA, et al. Effect of carpaine, a papaya alkaloid, on the circulatory function in the rat. Res Commun Chem Pathol Pharmacol. 1978 Nov;22(2):277-89.

Molecular Formula	C₂₈H₅₁ClN₂O₄
Molecular Weight	515.17