2340020-82-6

2340020-82-6 structure
2340020-82-6 structure
  • Name: RAF mutant-IN-1
  • Chemical Name: RAF mutant-IN-1
  • CAS Number: 2340020-82-6
  • Molecular Formula: C23H18Cl3FN6O2S
  • Molecular Weight: 567.85
  • Catalog: Signaling Pathways MAPK/ERK Pathway Raf
  • Create Date: 2019-10-09 13:09:29
  • Modify Date: 2025-08-27 16:52:35
  • RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].

Name RAF mutant-IN-1
Description RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
Related Catalog
Target

C-RAF 340D/Y341D:21 nM (IC50)

B-RafV600E:30 nM (IC50)

BRAFWT:392 nM (IC50)

References

[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.

Molecular Formula C23H18Cl3FN6O2S
Molecular Weight 567.85
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