RAF mutant-IN-1

Modify Date: 2025-08-27 16:52:35

RAF mutant-IN-1 structure	Common Name	RAF mutant-IN-1
	CAS Number	2340020-82-6	Molecular Weight	567.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₈Cl₃FN₆O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RAF mutant-IN-1

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].

Name	RAF mutant-IN-1

Description	RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	C-RAF 340D/Y341D:21 nM (IC50) B-RafV600E:30 nM (IC50) BRAFWT:392 nM (IC50)
References	[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.

Molecular Formula	C₂₃H₁₈Cl₃FN₆O₂S
Molecular Weight	567.85
InChIKey	LUOSZUYSWJVQGN-UHFFFAOYSA-N
SMILES	Cc1ccc2c(Nc3ccc(O)c(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12.Cl.Cl

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China
Product Name: RAF mutant-IN-1
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Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.