2247236-59-3
2247236-59-3 structure
- Name: BY27
- Chemical Name: BY27
- CAS Number: 2247236-59-3
- Molecular Formula: C22H21ClN6
- Molecular Weight: 404.90
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2019-10-09 09:21:29
- Modify Date: 2024-11-27 22:48:24
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BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity[1].
| Name | BY27 |
|---|
| Description | BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity[1]. |
|---|---|
| Related Catalog | |
| Target |
BRD2 BD2:3.1 nM (Ki) BRD2 BD1:95.5 nM (Ki) BRD3 BD2:5.3 nM (Ki) BRD3 BD1:77.9 nM (Ki) BRD4 BD2:7.3 nM (Ki) BRD4 BD1:80 nM (Ki) BRD2 BD2:1.2 nM (Kd) BRD2 BD1:45 nM (Kd) BRD3 BD2:2.6 nM (Kd) BRD3 BD1:12 nM (Kd) BRD4 BD2:3.5 nM (Kd) BRD4 BD1:26 nM (Kd) BRDT BD2:3 nM (Kd) BRDT BD1:64 nM (Kd) |
| References |
| Molecular Formula | C22H21ClN6 |
|---|---|
| Molecular Weight | 404.90 |