1207560-07-3

1207560-07-3 structure

1207560-07-3 structure

Name: Sorafenib-d4
Chemical Name: Sorafenib (D4)
CAS Number: 1207560-07-3
Molecular Formula: C₂₁H₁₂D₄ClF₃N₄O₃
Molecular Weight: 468.85
Catalog: Research Areas Others
Create Date: 2019-09-07 17:26:16
Modify Date: 2024-01-05 11:55:04
Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.

Name	Sorafenib (D4)

Description	Sorafenib D4 (Bay 43-9006 D4) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Wilhelm SM, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 2004 Oct 1;64(19):7099-109.

Molecular Formula	C₂₁H₁₂D₄ClF₃N₄O₃
Molecular Weight	468.85