DC Chemicals Limited
China
Product Name: KT185
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1472640-86-0

1472640-86-0 structure

1472640-86-0 structure

Name: KT185
Chemical Name: KT185
CAS Number: 1472640-86-0
Molecular Formula: C₃₂H₃₃N₅O₂
Molecular Weight: 519.64
Catalog: Signaling Pathways Metabolic Enzyme/Protease MAGL
Create Date: 2019-08-03 20:42:59
Modify Date: 2024-01-16 19:53:26
KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].

Name	KT185

Description	KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL
Target	IC50: ABHD6 (0.21 nM in Neuro2A cells)[1].
References	[1]. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.

Molecular Formula	C₃₂H₃₃N₅O₂
Molecular Weight	519.64

RIDADR	NONH for all modes of transport