1438284-00-4

1438284-00-4 structure

1438284-00-4 structure

Name: JAK2-IN-4
Chemical Name: JAK2-IN-4
CAS Number: 1438284-00-4
Molecular Formula: C₂₃H₂₇N₅O₄S
Molecular Weight: 469.56
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2019-08-03 22:20:58
Modify Date: 2024-01-23 17:59:48
JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1].

Name	JAK2-IN-4

Description	JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Others
Target	IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1].
References	[1]. Wang Y, et al. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg Med Chem. 2017 Jan 1;25(1):75-83.

Molecular Formula	C₂₃H₂₇N₅O₄S
Molecular Weight	469.56