306305-07-7

306305-07-7 structure

Name: 4'-Ethynyl-2'-deoxyadenosine
Chemical Name: 4'-Ethynyl-2'-deoxyadenosine
CAS Number: 306305-07-7
Molecular Formula: C₁₂H₁₃N₅O₃
Molecular Weight: 275.26
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2019-08-03 21:15:58
Modify Date: 2025-09-29 23:09:04
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1].

Name	4'-Ethynyl-2'-deoxyadenosine

Description	4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Reverse Transcriptase
Target	EC50: 98 nM (MT-4 cells)[1].
References	[1]. Ohrui H, et al. 4'-C-substituted-2'-deoxynucleosides: a family of antiretroviral agents which are potent against drug-resistant HIV variants. Curr Drug Targets Infect Disord. 2001 May;1(1):1-10.

Molecular Formula	C₁₂H₁₃N₅O₃
Molecular Weight	275.26

Hazard Codes	Xi