Top Suppliers:I want be here


921605-87-0

921605-87-0 structure
921605-87-0 structure

Name MF-438
Description MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1[1].
Related Catalog
Target

EC50: 2.3 nM (rSCD1)[1]

In Vivo MF-438 exhibits an ED50 between 1 and 3 mg/kg in a mouse model[1].
References

[1]. Léger S, et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). Bioorg Med Chem Lett. 2010 Jan 15;20(2):499-502.

Molecular Formula C19H18F3N5OS
Molecular Weight 421.44