1810769-31-3
1810769-31-3 structure
- Name: Mcl1-IN-9
- Chemical Name: Mcl1-IN-9
- CAS Number: 1810769-31-3
- Molecular Formula: C37H39ClN4O4
- Molecular Weight: 639.18
- Catalog: Signaling Pathways Apoptosis Bcl-2 Family
- Create Date: 2019-06-30 12:43:15
- Modify Date: 2024-01-05 12:40:25
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Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM[1].
| Name | Mcl1-IN-9 |
|---|
| Description | Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
Mcl-1:0.03 nM (Ki) |
| In Vitro | Mcl1-IN-9 inhibits growth of Mcl-1 dependent tumor cell lines in the nanomolar range[1]. |
| In Vivo | Mcl1-IN-9 inhibits the growth of hematological and triple negative breast cancer xenografts at well tolerated doses[1]. |
| References |
| Molecular Formula | C37H39ClN4O4 |
|---|---|
| Molecular Weight | 639.18 |