1380548-02-6

1380548-02-6 structure

Name: SR 10067
Chemical Name: SR10067
CAS Number: 1380548-02-6
Molecular Formula: C₃₁H₃₁NO₃
Molecular Weight: 465.58
Catalog: Research Areas Neurological Disease
Create Date: 2019-06-01 12:30:10
Modify Date: 2025-09-19 14:23:18
SR10067 is a potent, selective and brain penetrant Rev-Erbα/β agonist, with IC50 values are 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively. SR10067 has anxiolytic activity[1][2].

Name	SR10067

Description	SR10067 is a potent, selective and brain penetrant Rev-Erbα/β agonist, with IC50 values are 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively. SR10067 has anxiolytic activity[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	IC50: 160 nM (Rev-Erbβ), 170 nM (Rev-Erbα)[1].
References	[1]. Banerjee S, et al. Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour. Nat Commun. 2014 Dec 23;5:5759. doi: 10.1038/ncomms6759. [2]. Thevis M, et al. Emerging drugs affecting skeletal muscle function and mitochondrial biogenesis - Potential implications for sports drug testing programs. Rapid Commun Mass Spectrom. 2016 Mar 15;30(5):635-51.