2222354-61-0

2222354-61-0 structure
2222354-61-0 structure
  • Name: SNIPER(ABL)-058
  • Chemical Name: SNIPER(ABL)-058
  • CAS Number: 2222354-61-0
  • Molecular Formula: C62H75N11O9S
  • Molecular Weight: 1150.39
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
  • Create Date: 2019-06-01 21:10:17
  • Modify Date: 2025-08-27 09:17:01
  • SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].

Name SNIPER(ABL)-058
Description SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].
Related Catalog
References

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Molecular Formula C62H75N11O9S
Molecular Weight 1150.39
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