Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BI-1408
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2231075-94-6

2231075-94-6 structure

2231075-94-6 structure

Name: BI-1408
Chemical Name: BI-1408
CAS Number: 2231075-94-6
Molecular Formula: C₂₂H₂₃FN₆
Molecular Weight: 390.46
Catalog: Research Areas Neurological Disease
Create Date: 2019-06-02 10:38:56
Modify Date: 2025-08-27 14:02:20
BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].

Name	BI-1408

Description	BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42[1].
Related Catalog	Research Areas >> Neurological Disease
Target	IC50: 40 nM (Aβ42)[1]
References	[1]. Gerlach K, et al. Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators. Bioorg Med Chem. 2018 Jul 23;26(12):3227-3241.

Molecular Formula	C₂₂H₂₃FN₆
Molecular Weight	390.46

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