Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SJFδ
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Purity: 98.0%
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2254609-23-7

2254609-23-7 structure

2254609-23-7 structure

Name: SJFδ
Chemical Name: SJFδ
CAS Number: 2254609-23-7
Molecular Formula: C₆₂H₆₃F₂N₇O₁₂S
Molecular Weight: 1168.27
Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
Create Date: 2019-03-30 20:19:34
Modify Date: 2024-01-12 14:41:18
SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38α with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].

Name	SJFδ

Description	SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38α with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Signaling Pathways >> PROTAC >> PROTAC
Target	p38α:46.17 nM (DC50) PROTAC
References	[1]. Smith BE, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019 Jan 10;10(1):131.

Molecular Formula	C₆₂H₆₃F₂N₇O₁₂S
Molecular Weight	1168.27

Hazard Codes	Xi