2285346-31-6

2285346-31-6 structure

2285346-31-6 structure

Name: RTS-V5
Chemical Name: RTS-V5
CAS Number: 2285346-31-6
Molecular Formula: C₂₇H₃₅N₅O₆
Molecular Weight: 525.60
Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
Create Date: 2019-03-30 11:57:34
Modify Date: 2024-01-06 18:15:00
RTS-V5 is a dual HDAC/proteasome inhibitor with IC50s of 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively.

Name	RTS-V5

Description	RTS-V5 is a dual HDAC/proteasome inhibitor with IC50s of 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Signaling Pathways >> Epigenetics >> HDAC
Target	IC50: 6.9 nM (HDAC1), 18 nM (HDAC2), 15 nM (HDAC3), 0.27 nM (HDAC6), 0.53 nM (HDAC8)[1]
References	[1]. Bhatia S, et al. Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. J Med Chem. 2018 Nov 21;61(22):10299-10309.

Molecular Formula	C₂₇H₃₅N₅O₆
Molecular Weight	525.60