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2213468-64-3

2213468-64-3 structure
2213468-64-3 structure
  • Name: IIIM-290
  • Chemical Name: IIIM-290
  • CAS Number: 2213468-64-3
  • Molecular Formula: C23H21Cl2NO5
  • Molecular Weight: 462.32
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
  • Create Date: 2019-03-30 14:12:33
  • Modify Date: 2025-08-27 09:03:46
  • IIIM-290 is a potent and oral CDK inhibitor with IC50s of 90 and 94 nM for CDK2/A and CDK9/T1.

Name IIIM-290
Description IIIM-290 is a potent and oral CDK inhibitor with IC50s of 90 and 94 nM for CDK2/A and CDK9/T1.
Related Catalog
Target

CDK2/A:90 nM (IC50)

CDK9/T1:94 nM (IC50)

References

[1]. Bharate SB, et al. Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor. J Med Chem. 2018 Feb 22;61(4):1664-1687.

Molecular Formula C23H21Cl2NO5
Molecular Weight 462.32
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