1893415-00-3

1893415-00-3 structure

Name: AZD9567
Chemical Name: AZD9567
CAS Number: 1893415-00-3
Molecular Formula: C₂₇H₂₈F₂N₄O₃
Molecular Weight: 494.53
Catalog: Signaling Pathways GPCR/G Protein Glucocorticoid Receptor
Create Date: 2019-03-30 15:18:33
Modify Date: 2024-04-02 15:31:46
AZD9567 (compound 15) is a potent, selective and oral active non-steroidal glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].

Name	AZD9567

Description	AZD9567 (compound 15) is a potent, selective and oral active non-steroidal glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
Target	IC50: 3.8 nM (Glucocorticoid receptor)[1].
References	[1]. Ripa L, et al. Discovery of a Novel Oral Glucocorticoid Receptor Modulator (AZD9567) with Improved Side Effect Profile. J Med Chem. 2018 Mar 8;61(5):1785-1799.