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1370241-45-4

1370241-45-4 structure
1370241-45-4 structure
  • Name: RO-7
  • Chemical Name: RO-7
  • CAS Number: 1370241-45-4
  • Molecular Formula: C24H20F3N3O3S
  • Molecular Weight: 487.49
  • Catalog: Signaling Pathways Anti-infection Influenza Virus
  • Create Date: 2019-02-11 16:45:35
  • Modify Date: 2024-02-04 14:23:45
  • RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.

Name RO-7
Description RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses.
Related Catalog
In Vitro RO-7 is a compound that potently inhibits influenza virus replication and belongs to a new class of drugs in late-stage clinical trials for treatment of influenza virus infection. RO-7 displays broad-spectrum anti-influenza activity in vitro and protects mice from lethal challenge with both influenza A and B viruses[1].
In Vivo RO-7 protects mice from lethal challenge with both influenza A and B viruses[1].
References

[1]. Jones JC, et al. Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation InfluenzaVirus Endonuclease Inhibitors. MBio. 2018 Apr 24;9(2). pii: e00430-18.

Molecular Formula C24H20F3N3O3S
Molecular Weight 487.49