946525-65-1

946525-65-1 structure

Name: Velagliflozin
Chemical Name: velagliflozin
CAS Number: 946525-65-1
Molecular Formula: C₂₃H₂₅NO₅
Molecular Weight: 395.448
Catalog: Signaling Pathways Membrane Transporter/Ion Channel SGLT
Create Date: 2018-10-17 15:07:58
Modify Date: 2025-08-27 12:23:22
Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.

Name	velagliflozin
Synonyms	velagliflozin (1S)-1,5-Anhydro-1-[4-cyano-3-(4-cyclopropylbenzyl)phenyl]-D-glucitol UNII:FV2YU8SL0P D-Glucitol, 1,5-anhydro-1-C-[4-cyano-3-[(4-cyclopropylphenyl)methyl]phenyl]-, (1S)-

Description	Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> SGLT Research Areas >> Metabolic Disease
Target	SGLT2[1]
In Vitro	Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity[1].
In Vivo	Velagliflozin (1 mg/kg, p.o.) increases cholesterol, albumin, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), and urinary glucose excretion, and decreases respiratory exchange ratio in cats[1].
References	[1]. Hoenig M, et al. Effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor velagliflozin, a new drug with therapeutic potential to treat diabetes in cats. J Vet Pharmacol Ther. 2018 Apr;41(2):266-273.