154040-19-4

154040-19-4 structure
154040-19-4 structure
  • Name: α-Synuclein (61-95) (human) trifluoroacetate salt
  • Chemical Name: NAC
  • CAS Number: 154040-19-4
  • Molecular Formula: C141H235N39O49
  • Molecular Weight: 3260.61
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-07-04 15:16:21
  • Modify Date: 2024-01-02 13:36:04
  • α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].

Name NAC
Synonyms GLU-GLN-VAL-THR-ASN-VAL-GLY-GLY-ALA-VAL-VAL-THR-GLY-VAL-THR-ALA-VAL-ALA-GLN-LYS-THR-VAL-GLU-GLY-ALA-GLY-SER-ILE-ALA-ALA-ALA-THR-GLY-PHE-VAL
Description α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].
Related Catalog
References

[1]. Tabner BJ, et al. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic Biol Med. 2002 Jun 1;32(11):1076-83.  

[2]. Emadi S, et al. Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. Biochemistry. 2004 Mar 16;43(10):2871-8.

Density 1.3±0.1 g/cm3
Boiling Point 2937.7±65.0 °C at 760 mmHg
Molecular Formula C141H235N39O49
Molecular Weight 3260.61
Flash Point 1730.4±34.3 °C
Exact Mass 3258.709473
LogP -6.81
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.553
Storage condition −20°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3