60892-83-3

60892-83-3 structure

Name: Triolein-d5
Chemical Name: Glyceryl-d5 Trioleate
CAS Number: 60892-83-3
Molecular Formula: C₅₇H₉₉D₅O₆
Molecular Weight: 890.46
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2018-07-11 17:02:08
Modify Date: 2024-01-20 13:23:04
Triolein-d5 is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].

Name	Glyceryl-d5 Trioleate
Synonyms	9-Octadecenoic acid, 1,2,3-propanetriyl-d5 ester, (9Z,9'Z,9''Z)- (2H5)-1,2,3-Propanetriyl (9Z,9'Z,9''Z)tris(-9-octadecenoate)

Description	Triolein-d5 is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Leirós GJ, et al. Triolein reduces MMP-1 upregulation in dermal fibroblasts generated by ROS production in UVB-irradiated keratinocytes. J Dermatol Sci. 2017 Feb;85(2):124-130.