2098487-39-7

2098487-39-7 structure

Name: Thalidomide, propargyl
Chemical Name: 2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
CAS Number: 2098487-39-7
Molecular Formula: C₁₆H₁₂N₂O₅
Molecular Weight: 312.27688
Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
Create Date: 2018-06-03 04:26:29
Modify Date: 2025-08-27 12:03:19
Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs[1].

Name	2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione

Description	Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for protein by a linker to form the IMiD containing PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	Cereblon
References	[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.

Molecular Formula	C₁₆H₁₂N₂O₅
Molecular Weight	312.27688

Hazard Codes	Xi