1818294-35-7
1818294-35-7 structure
- Name: Fluorescein-PEG6- NHS ester
- Chemical Name: Fluorescein-PEG6-NHS ester
- CAS Number: 1818294-35-7
- Molecular Formula: C40H45N3O15S
- Molecular Weight: 839.861
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-18 00:06:51
- Modify Date: 2024-01-11 13:11:00
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Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Fluorescein-PEG6-NHS ester |
|---|---|
| Synonyms |
5-[({21-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-21-oxo-3,6,9,12,15,18-hexaoxahenicos-1-yl}carbamothioyl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
Benzoic acid, 5-[[23-[(2,5-dioxo-1-pyrrolidinyl)oxy]-23-oxo-1-thioxo-5,8,11,14,17,20-hexaoxa-2-azatricos-1-yl]amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)- MFCD23726632 |
| Description | Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 976.2±75.0 °C at 760 mmHg |
| Molecular Formula | C40H45N3O15S |
| Molecular Weight | 839.861 |
| Flash Point | 544.2±37.1 °C |
| Exact Mass | 839.257141 |
| LogP | -1.08 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.649 |