145731-49-3

145731-49-3 structure
145731-49-3 structure
  • Name: Z-L-Abu-CONH(CH2)3-morpholine
  • Chemical Name: CALPAIN INHIBITOR XI
  • CAS Number: 145731-49-3
  • Molecular Formula: C19H29N3O4
  • Molecular Weight: 363.45
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Proteasome
  • Create Date: 2018-06-11 23:30:40
  • Modify Date: 2024-09-14 15:03:11
  • Calpain Inhibitor XI is a reversible covalent inhibitor of calpain-1. Calpain Inhibitor XI can be used for the research of neurodegenerative disorders[1].

Name CALPAIN INHIBITOR XI
Description Calpain Inhibitor XI is a reversible covalent inhibitor of calpain-1. Calpain Inhibitor XI can be used for the research of neurodegenerative disorders[1].
Related Catalog
In Vitro Calpain inhibitor XI (CaXI) (1 μM) can inhibit calpain-1, cathepsin-K and also modestly inhibits (∼20%) both papain and cathepsin-B[1].
References

[1]. Rachel C Knopp, et al. Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma. ACS Pharmacol Transl Sci. 2021 Feb 2;4(1):372-385.  

Molecular Formula C19H29N3O4
Molecular Weight 363.45