Name | H2N-PEG12-tBu |
---|---|
Synonyms |
MFCD11041147
3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxanonatriacontan-39-oic acid, 1-amino-, 1,1-dimethylethyl ester 2-Methyl-2-propanyl 1-amino-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxanonatriacontan-39-oate |
Description | Amino-PEG12-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 665.0±50.0 °C at 760 mmHg |
Molecular Formula | C31H63NO14 |
Molecular Weight | 673.830 |
Flash Point | 59.5±26.4 °C |
Exact Mass | 673.424866 |
LogP | -3.10 |
Vapour Pressure | 0.0±2.0 mmHg at 25°C |
Index of Refraction | 1.463 |