1043491-54-8

1043491-54-8 structure

Name: RO 5203648
Chemical Name: RO-5203648
CAS Number: 1043491-54-8
Molecular Formula: C₉H₈Cl₂N₂O
Molecular Weight: 231.08
Catalog: Research Areas Neurological Disease
Create Date: 2018-06-26 02:41:27
Modify Date: 2025-08-26 05:45:34
RO5203648 is a potent and highly selective partial agonist of TAAR1 (Trace amine-associated receptor 1) with high affinity. RO5203648 demonstrates a novel paradigm for neuropsychiatric therapeutics[1].

Name	RO-5203648
Synonyms	(4S)-4-(3,4-Dichlorophenyl)-4,5-dihydro-1,3-oxazol-2-amine 2-Oxazolamine, 4-(3,4-dichlorophenyl)-4,5-dihydro-, (4S)-

Description	RO5203648 is a potent and highly selective partial agonist of TAAR1 (Trace amine-associated receptor 1) with high affinity. RO5203648 demonstrates a novel paradigm for neuropsychiatric therapeutics[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Revel FG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biol Psychiatry. 2012 Dec 1;72(11):934-42.