1227069-12-6

1227069-12-6 structure
1227069-12-6 structure
  • Name: 2′-Deoxy-N-(2-furanylmethyl)guanosine
  • Chemical Name: 2'-Deoxy-N-(2-furylmethyl)guanosine
  • CAS Number: 1227069-12-6
  • Molecular Formula: C15H17N5O5
  • Molecular Weight: 347.33
  • Catalog: Research Areas Others
  • Create Date: 2018-06-29 05:13:10
  • Modify Date: 2024-01-13 13:42:50
  • 2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name 2'-Deoxy-N-(2-furylmethyl)guanosine
Synonyms 2'-Deoxy-N-(2-furylmethyl)guanosine
Guanosine, 2'-deoxy-N-(2-furanylmethyl)-
Description 2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog
References

[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.  

Density 1.8±0.1 g/cm3
Molecular Formula C15H17N5O5
Molecular Weight 347.33
Exact Mass 347.122955
LogP -1.79
Index of Refraction 1.798