1394156-45-6
1394156-45-6 structure
- Name: 8α-Hydroxyhirsutinolide
- Chemical Name: (1R,2E,8S,10R,11S)-8,11-Dihydroxy-6-(hydroxymethyl)-1,10-dimethyl-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-5-one
- CAS Number: 1394156-45-6
- Molecular Formula: C15H20O6
- Molecular Weight: 296.32
- Catalog: Natural product Sesquiter
- Create Date: 2018-07-09 22:07:28
- Modify Date: 2025-08-25 14:20:33
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8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC50: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea[1].
| Name | (1R,2E,8S,10R,11S)-8,11-Dihydroxy-6-(hydroxymethyl)-1,10-dimethyl-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-5-one |
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| Synonyms |
(1R,2E,8S,10R,11S)-8,11-Dihydroxy-6-(hydroxymethyl)-1,10-dimethyl-4,14-dioxatricyclo[9.2.1.03,7]tetradeca-2,6-dien-5-one
7,10-Epoxycyclodeca[b]furan-2(4H)-one, 5,6,7,8,9,10-hexahydro-4,7-dihydroxy-3-(hydroxymethyl)-6,10-dimethyl-, (4S,6R,7S,10R,11E)- |
| Description | 8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC50: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 587.4±50.0 °C at 760 mmHg |
| Molecular Formula | C15H20O6 |
| Molecular Weight | 296.32 |
| Flash Point | 222.7±23.6 °C |
| Exact Mass | 296.125977 |
| LogP | 0.51 |
| Vapour Pressure | 0.0±3.7 mmHg at 25°C |
| Index of Refraction | 1.610 |
| Storage condition | 2-8℃ |
| Hazard Codes | Xi |
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