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22255-13-6

22255-13-6 structure
22255-13-6 structure
  • Name: Guaijaverin
  • Chemical Name: Guaijaverin
  • CAS Number: 22255-13-6
  • Molecular Formula: C20H18O11
  • Molecular Weight: 434.350
  • Catalog: Natural product Flavonoids
  • Create Date: 2018-05-02 08:00:00
  • Modify Date: 2025-08-25 14:29:39
  • Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities[1][2][3].
Name Guaijaverin
Synonyms 3-(α-L-Arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
Quercetin-3-Arabinoside
4H-1-Benzopyran-4-one, 3-(α-L-arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-
Quercetin 3-O-α-L-arabinoside
3-(alpha-L-Arabinopyranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl α-L-arabinopyranoside
Quercetin 3-O-alpha-L-arabinoside
Description Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities[1][2][3].
Related Catalog
Target

IC50: 120 μM (Urease)[1]

In Vitro Guaijaverin has anti-Strep.mutans activity, with MIC values of 4 and 2 mg/ml for MTCC 1943 and CLSM 001 strain of Strep. mutans, respectively[3].
References

[1]. Shabana S, et al. Inhibitory activity against urease of quercetin glycosides isolated from Allium cepa and Psidium guajava. Biosci Biotechnol Biochem. 2010;74(4):878-80.

[2]. Caruso IP, et al. Exploring the binding mechanism of Guaijaverin to human serum albumin: fluorescencespectroscopy and computational approach. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Nov;97:449-55.

[3]. Prabu GR, et al. Guaijaverin -- a plant flavonoid as potential antiplaque agent against Streptococcus mutans. J Appl Microbiol. 2006 Aug;101(2):487-95.
Density 1.9±0.1 g/cm3
Boiling Point 828.1±65.0 °C at 760 mmHg
Molecular Formula C20H18O11
Molecular Weight 434.350
Flash Point 296.3±27.8 °C
Exact Mass 434.084900
PSA 190.28000
LogP 1.68
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.802
Storage condition room temp
RIDADR NONH for all modes of transport
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title: CAS No. 22255-13-6 | Chemsrc address: https://www.chemsrc.com/en/baike/151764.html

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