340007-39-8

340007-39-8 structure

Name: GID4 Ligand 3
Chemical Name: 3-[(5-Methyl-4,5-dihydro-1,3-thiazol-2-yl)amino]phenol
CAS Number: 340007-39-8
Molecular Formula: C₁₀H₁₂N₂OS
Molecular Weight: 208.280
Catalog: Research Areas Cancer
Create Date: 2018-06-07 15:09:38
Modify Date: 2025-09-29 16:19:16
GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC50 value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau[1].

Name	3-[(5-Methyl-4,5-dihydro-1,3-thiazol-2-yl)amino]phenol
Synonyms	3-[(5-Methyl-4,5-dihydro-1,3-thiazol-2-yl)amino]phenol Phenol, 3-[(4,5-dihydro-5-methyl-2-thiazolyl)amino]- MFCD01655227

Description	GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC50 value of 148.5 μM. GID4 Ligand 3 can be used for the research related to cereblon and Von Hippel-Lindau[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 148.5 μM (GID4)[1]
In Vitro	GID4 Ligand 3 (0-1000 μM; 30 min) binds with GID4 with a Kd value of 110 μM[1].
References	[1]. Chana CK, et al. Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4. J Med Chem. 2022 Sep 18.