217658-18-9

217658-18-9 structure

Name: Z-Ala-Pro-Phe-chloromethylketone
Chemical Name: N-[(Benzyloxy)carbonyl]-L-alanyl-N-[(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]-L-prolinamide
CAS Number: 217658-18-9
Molecular Formula: C₂₆H₃₀ClN₃O₅
Molecular Weight: 499.987
Catalog: Research Areas Others
Create Date: 2018-07-21 01:20:21
Modify Date: 2025-08-21 17:48:27
Z-APF-CMK is a specific inhibitor of Ca2+-regulated nuclear scaffold protease (CRNSP)[1].

Name	N-[(Benzyloxy)carbonyl]-L-alanyl-N-[(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]-L-prolinamide
Synonyms	L-Prolinamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]- N-[(Benzyloxy)carbonyl]-L-alanyl-N-[(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]-L-prolinamide

Description	Z-APF-CMK is a specific inhibitor of Ca2+-regulated nuclear scaffold protease (CRNSP)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Zhang D, et al. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis. Proc Natl Acad Sci U S A. 2001 May 8;98(10):5746-51.