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217817-09-9

217817-09-9 structure
217817-09-9 structure
  • Name: Curcolonol
  • Chemical Name: (4aR,5R,8R,8aR)-5,8-Dihydroxy-3,5,8a-trimethyl-5,6,7,8,8a,9-hexahydronaphtho[2,3-b]furan-4(4aH)-one
  • CAS Number: 217817-09-9
  • Molecular Formula: C15H20O4
  • Molecular Weight: 264.317
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage LIM Kinase (LIMK)
  • Create Date: 2018-06-27 06:53:51
  • Modify Date: 2024-01-30 09:39:02
  • Curcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for LIM kinase 1. Curcolonol can be used for the research of breast cancer[1].

Name (4aR,5R,8R,8aR)-5,8-Dihydroxy-3,5,8a-trimethyl-5,6,7,8,8a,9-hexahydronaphtho[2,3-b]furan-4(4aH)-one
Synonyms (4aR,5R,8R,8aR)-5,8-Dihydroxy-3,5,8a-trimethyl-5,6,7,8,8a,9-hexahydronaphtho[2,3-b]furan-4(4aH)-one
Naphtho[2,3-b]furan-4(4aH)-one, 5,6,7,8,8a,9-hexahydro-5,8-dihydroxy-3,5,8a-trimethyl-, (4aR,5R,8R,8aR)-
Description Curcolonol is a furan type sesquiterpene. Curcolonol can be isolated from several medical herbs. Curcolonol has inhibitory activity for LIM kinase 1. Curcolonol can be used for the research of breast cancer[1].
Related Catalog
References

[1]. Hong Lu, et al. Curcolonol suppresses the motility of breast cancer cells by inhibiting LIM kinase 1 to downregulate cofilin 1 phosphorylation. Int J Oncol. 2018 Dec;53(6):2695-2704.  

Density 1.3±0.1 g/cm3
Boiling Point 424.8±45.0 °C at 760 mmHg
Molecular Formula C15H20O4
Molecular Weight 264.317
Flash Point 210.7±28.7 °C
Exact Mass 264.136169
LogP 2.35
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.570
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