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139262-76-3

139262-76-3 structure
139262-76-3 structure
  • Name: H2L5186303
  • Chemical Name: (2Z,2'Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis(4-oxo-2-butenoic acid)
  • CAS Number: 139262-76-3
  • Molecular Formula: C26H20N2O8
  • Molecular Weight: 488.446
  • Create Date: 2018-06-22 04:19:55
  • Modify Date: 2025-08-25 20:45:42
  • H2L5186303 is a potent and selective LPA2 receptor (lysophosphatidic acid 2 receptor) antagonist with an IC50 of 9 nM[1].

Name (2Z,2'Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis(4-oxo-2-butenoic acid)
Synonyms 2-Butenoic acid, 4,4'-[1,3-phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-, (2Z,2'Z)-
(2Z,2'Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis(4-oxo-2-butenoic acid)
Description H2L5186303 is a potent and selective LPA2 receptor (lysophosphatidic acid 2 receptor) antagonist with an IC50 of 9 nM[1].
Related Catalog
Target

LPA2 Receptor:9 nM (IC50)

References

[1]. Fells JI, et al. Structure-based drug design identifies novel LPA3 antagonists. Bioorg Med Chem. 2009 Nov 1;17(21):7457-64.

Density 1.4±0.1 g/cm3
Boiling Point 801.0±65.0 °C at 760 mmHg
Molecular Formula C26H20N2O8
Molecular Weight 488.446
Flash Point 438.2±34.3 °C
Exact Mass 488.121979
LogP 4.46
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.688
Storage condition 2-8°C
RIDADR NONH for all modes of transport
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