1353676-65-9

1353676-65-9 structure

Name: 5,7,3',4'-Tetrahydroxy-3-Methoxy-8,5'-diprenylflavone
Chemical Name: 2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
CAS Number: 1353676-65-9
Molecular Formula: C₂₆H₂₈O₇
Molecular Weight: 452.496
Catalog: Natural product Flavonoids
Create Date: 2018-07-13 06:24:59
Modify Date: 2023-01-27 07:11:35
5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].

Name	2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
Synonyms	4H-1-Benzopyran-4-one, 2-[3,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)- 2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one

Description	5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. FujiangGuo, et al. Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo. Phytochemistry Letters. Volume 6, Issue 3, August 2013, Pages 331-336.

Hazard Codes	Xi