126433-07-6
126433-07-6 structure
- Name: Tyrphostin 51
- Chemical Name: (3Z)-2-Amino-4-(3,4,5-trihydroxyphenyl)-1,3-butadiene-1,1,3-tricarbonitrile
- CAS Number: 126433-07-6
- Molecular Formula: C13H8N4O3
- Molecular Weight: 268.228
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2018-07-10 22:25:25
- Modify Date: 2024-01-13 18:07:49
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Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation[1][2].
| Name | (3Z)-2-Amino-4-(3,4,5-trihydroxyphenyl)-1,3-butadiene-1,1,3-tricarbonitrile |
|---|---|
| Synonyms |
MFCD00133903
1,3-Butadiene-1,1,3-tricarbonitrile, 2-amino-4-(3,4,5-trihydroxyphenyl)-, (3Z)- 1,3-Butadiene-1,1,3-tricarbonitrile, 2-amino-4-(3,4,5-trihydroxyphenyl)-, (Z)- (3Z)-2-Amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile (3Z)-2-Amino-4-(3,4,5-trihydroxyphenyl)-1,3-butadiene-1,1,3-tricarbonitrile |
| Description | Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [3H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 788.2±60.0 °C at 760 mmHg |
| Molecular Formula | C13H8N4O3 |
| Molecular Weight | 268.228 |
| Flash Point | 430.5±32.9 °C |
| Exact Mass | 268.059631 |
| LogP | 0.04 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.757 |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |