1095004-78-6
1095004-78-6 structure
- Name: AZD7624
- Chemical Name: 3P4CR02JTD
- CAS Number: 1095004-78-6
- Molecular Formula: C27H30FN5O3
- Molecular Weight: 491.557
- Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
- Create Date: 2018-07-03 23:41:49
- Modify Date: 2024-01-09 21:52:40
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AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
| Name | 3P4CR02JTD |
|---|---|
| Synonyms |
N-Cyclopropyl-3-fluoro-4-methyl-5-{3-[(1-{2-[2-(methylamino)ethoxy]phenyl}cyclopropyl)amino]-2-oxo-1(2H)-pyrazinyl}benzamide
Benzamide, N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]- 3P4CR02JTD AZD7624 |
| Description | AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity. |
|---|---|
| Related Catalog | |
| Target |
p38[1] |
| In Vitro | AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity. AZD7624 inhibits LPS-induced TNFα in human mononuclear cells, in whole blood as well as in alveolar macrophages in vitro, with pIC50u of 8.4, 8.7, and 9.0[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H30FN5O3 |
| Molecular Weight | 491.557 |
| Exact Mass | 491.233276 |
| LogP | 1.59 |
| Index of Refraction | 1.661 |