158665-47-5

158665-47-5 structure

Name: 2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine
Chemical Name: 2'-Amino-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine
CAS Number: 158665-47-5
Molecular Formula: C₃₁H₃₃N₃O₇
Molecular Weight: 559.61
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-14 17:11:03
Modify Date: 2024-01-06 22:39:03
2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Amino-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine
Synonyms	Thymidine, 2'-amino-5'-O-[bis(4-methoxyphenyl)phenylmethyl]- 2'-Amino-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine

Description	2’-Amino-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.