1421933-37-0
1421933-37-0 structure
- Name: Mal-PEG4-OH
- Chemical Name: 1-(2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}ethyl)-1H-pyrrole-2,5-dione
- CAS Number: 1421933-37-0
- Molecular Formula: C12H19NO6
- Molecular Weight: 273.282
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-29 21:27:04
- Modify Date: 2024-01-02 17:14:57
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Mal-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 1-(2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}ethyl)-1H-pyrrole-2,5-dione |
|---|---|
| Synonyms |
1-(2-{2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy}ethyl)-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]- |
| Description | Mal-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 427.9±35.0 °C at 760 mmHg |
| Molecular Formula | C12H19NO6 |
| Molecular Weight | 273.282 |
| Flash Point | 212.6±25.9 °C |
| Exact Mass | 273.121246 |
| LogP | -1.61 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.512 |