1421932-52-6
1421932-52-6 structure
- Name: endo-BCN-PEG4-PFP ester
- Chemical Name: Pentafluorophenyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate
- CAS Number: 1421932-52-6
- Molecular Formula: C28H34F5NO8
- Molecular Weight: 607.563
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-04 10:38:56
- Modify Date: 2024-01-12 21:48:56
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endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Pentafluorophenyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate |
|---|---|
| Synonyms |
Pentafluorophenyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate
2,7,10,13,16-Pentaoxa-4-azanonadecan-19-oic acid, 1-bicyclo[6.1.0]non-4-yn-9-yl-3-oxo-, 2,3,4,5,6-pentafluorophenyl ester |
| Description | endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 650.9±55.0 °C at 760 mmHg |
| Molecular Formula | C28H34F5NO8 |
| Molecular Weight | 607.563 |
| Flash Point | 347.5±31.5 °C |
| Exact Mass | 607.220459 |
| LogP | 3.45 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.515 |