935279-95-1

935279-95-1 structure
935279-95-1 structure
  • Name: DAM-IN-1
  • Chemical Name: 4-(Ethoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid
  • CAS Number: 935279-95-1
  • Molecular Formula: C16H17NO4
  • Molecular Weight: 287.310
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
  • Create Date: 2018-07-03 10:39:03
  • Modify Date: 2024-02-07 16:20:09
  • DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor, IC50: 48 μM. DMA-IN-1 inhibits Caulobacter growth with an MIC of 35 μM[1].

Name 4-(Ethoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid
Synonyms 4-(Ethoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylic acid
3H-Cyclopenta[c]quinoline-4,8-dicarboxylic acid, 3a,4,5,9b-tetrahydro-, 4-ethyl ester
Description DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor, IC50: 48 μM. DMA-IN-1 inhibits Caulobacter growth with an MIC of 35 μM[1].
Related Catalog
Target

IC50: 48 μM (DNA adenine methyltransferase, DAM)[1]

References

[1]. Mashhoon N, et al. Selective inhibitors of bacterial DNA adenine methyltransferases. J Biomol Screen. 2006 Aug;11(5):497-510.  

Density 1.3±0.1 g/cm3
Boiling Point 447.3±45.0 °C at 760 mmHg
Molecular Formula C16H17NO4
Molecular Weight 287.310
Flash Point 224.3±28.7 °C
Exact Mass 287.115753
LogP 2.85
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.584
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