775289-20-8

775289-20-8 structure

Name: Caspase-3/7 Inhibitor II
Chemical Name: N-Acetyl-L-α-aspartyl-L-asparaginyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-leucinamide
CAS Number: 775289-20-8
Molecular Formula: C₂₀H₃₁N₅O₁₀
Molecular Weight: 501.488
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2018-07-04 05:19:42
Modify Date: 2025-08-25 16:56:28
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases[1].

Name	N-Acetyl-L-α-aspartyl-L-asparaginyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-leucinamide
Synonyms	L-Leucinamide, N-acetyl-L-α-aspartyl-L-asparaginyl-N-[(1S)-2-carboxy-1-formylethyl]- N-Acetyl-L-α-aspartyl-L-asparaginyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-leucinamide

Description	Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a Caspase-3/7 inhibitor (IC50: 9.89, 245 nM respectively; Kiapp: 0.68, 55.7 nM respectively). Ac-DNLD-CHO can be used for research of caspase-mediated apoptosis diseases, such as neurodegenerative disorders and viral infection diseases[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Neurological Disease
Target	Caspase-3/7[1]
References	[1]. Yoshimori A, et al. Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO. BMC Pharmacol. 2007 Jun 27;7:8.