1604034-78-7
1604034-78-7 structure
- Name: PF-05388169
- Chemical Name: 2-Methoxy-3-[2-(2-methoxyethoxy)ethoxy]-7H-indolo[2,3-c]quinoline-9-carbonitrile
- CAS Number: 1604034-78-7
- Molecular Formula: C22H21N3O4
- Molecular Weight: 391.420
- Create Date: 2018-06-26 16:40:59
- Modify Date: 2024-09-21 21:40:18
-
A potent, selective IRAK4 inhibitor with IC50 of 0.094 nM, >500-fold selectivity over IRAK1 (IC50=65 nM).
| Name | 2-Methoxy-3-[2-(2-methoxyethoxy)ethoxy]-7H-indolo[2,3-c]quinoline-9-carbonitrile |
|---|---|
| Synonyms |
7H-Indolo[2,3-c]quinoline-9-carbonitrile, 2-methoxy-3-[2-(2-methoxyethoxy)ethoxy]-
2-Methoxy-3-[2-(2-methoxyethoxy)ethoxy]-7H-indolo[2,3-c]quinoline-9-carbonitrile PF-05388169 |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 640.7±55.0 °C at 760 mmHg |
| Molecular Formula | C22H21N3O4 |
| Molecular Weight | 391.420 |
| Flash Point | 341.3±31.5 °C |
| Exact Mass | 391.153198 |
| LogP | 2.58 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.672 |