108392-27-4

108392-27-4 structure

Name: Suc-Ala-Ala-Pro-Abu-pNA trifluoroacetate salt
Chemical Name: N-(3-Carboxypropanoyl)-L-alanyl-L-alanyl-N-{(2S)-1-[(4-nitrophenyl)amino]-1-oxo-2-butanyl}-L-prolinamide
CAS Number: 108392-27-4
Molecular Formula: C₂₅H₃₄N₆O₉
Molecular Weight: 562.572
Catalog: Signaling Pathways Metabolic Enzyme/Protease Elastase
Create Date: 2018-06-16 19:45:33
Modify Date: 2024-03-05 18:06:47
Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration[1].

Name	N-(3-Carboxypropanoyl)-L-alanyl-L-alanyl-N-{(2S)-1-[(4-nitrophenyl)amino]-1-oxo-2-butanyl}-L-prolinamide
Synonyms	N-(3-Carboxypropanoyl)-L-alanyl-L-alanyl-N-{(2S)-1-[(4-nitrophenyl)amino]-1-oxo-2-butanyl}-L-prolinamide L-Prolinamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-[(1S)-1-[[(4-nitrophenyl)amino]carbonyl]propyl]-

Description	Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Elastase
References	[1]. Largman C. Isolation and characterization of rat pancreatic elastase. Biochemistry. 1983 Aug 2;22(16):3763-70.