54483-84-0

54483-84-0 structure

Name: 3α-Dihydrocadambine
Chemical Name: 3a-Dihydrocadambine
CAS Number: 54483-84-0
Molecular Formula: C₂₇H₃₄N₂O₁₀
Molecular Weight: 546.57
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-06-04 11:45:39
Modify Date: 2024-01-17 14:23:45
3α-Dihydrocadambine is a natural product isolated from the heartwoods of Anthocephalus cadamba.3α-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats[1][2].

Name	3a-Dihydrocadambine
Synonyms	3α-Dihydrocadambine Methyl (4S,4aS,5S,14bS,15aS)-4-(β-D-glucopyranosyloxy)-5-hydroxy-4,4a,5,6,8,9,14,14b,15,15a-decahydropyrano[4'',3'':4',5']azepino[1',2':1,2]pyrido[3,4-b]indole-1-carboxylate Pyrano[4'',3'':4',5']azepino[1',2':1,2]pyrido[3,4-b]indole-1-carboxylic acid, 4-(β-D-glucopyranosyloxy)-4,4a,5,6,8,9,14,14b,15,15a-decahydro-5-hydroxy-, methyl ester, (4S,4aS,5S,14bS,15aS)- 3a-Dihydrocadambine

Description	3α-Dihydrocadambine is a natural product isolated from the heartwoods of Anthocephalus cadamba.3α-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Takayama H, et al. Gluco-indole alkaloids from Nauclea cadamba in Thailand and transformation of 3 alpha-dihydrocadambine into the indolopyridine alkaloid, 16-carbomethoxynaufoline. Chem Pharm Bull (Tokyo). 2003;51(2):232-233. [2]. K Aisaka, et al. Hypotensive action of 3 alpha-dihydrocadambine, an indole alkaloid glycoside of Uncaria hooks. Planta Med. 1985 Oct;51(5):424-7.

Hazard Codes	Xi