672926-32-8

672926-32-8 structure

Name: Kif15-IN-1
Chemical Name: Kif15-IN-1
CAS Number: 672926-32-8
Molecular Formula: C₂₀H₂₂N₄O₅S
Molecular Weight: 430.478
Catalog: Signaling Pathways Cell Cycle/DNA Damage Kinesin
Create Date: 2018-01-21 19:46:19
Modify Date: 2025-08-25 18:02:05
Kif15-IN-1 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.

Name	Kif15-IN-1
Synonyms	5-Thiazolecarboxylic acid, 2-[[(2S)-2-(1,4-dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-, ethyl ester Ethyl 2-{[(2S)-2-(2,4-dioxo-1,4-dihydro-3(2H)-quinazolinyl)-3-methylbutanoyl]amino}-4-methyl-1,3-thiazole-5-carboxylate

Description	Kif15-IN-1 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Kinesin Signaling Pathways >> Cytoskeleton >> Kinesin Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology
Target	KIF15
In Vitro	Kif15-IN-1 (Compound 10) is an inhibitor of the mitotic kinesin Hs Kif15, with the potential activities against cellular proliferative diseases such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation[1].
References	[1]. Preparation of quinazolinediones as Kif15 kinesin inhibitors for treating cellular proliferative disorders. Pat. Appl. Publ. (2004), US 20040053948 A1 20040318.