364071-16-9

364071-16-9 structure

Name: OT-R antagonist 2
Chemical Name: OT-R antagonist 2
CAS Number: 364071-16-9
Molecular Formula: C₂₈H₂₉N₃O₄
Molecular Weight: 471.548
Catalog: Signaling Pathways GPCR/G Protein Oxytocin Receptor
Create Date: 2018-05-24 13:55:15
Modify Date: 2024-01-11 11:42:03
OT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).IC50 value: 0.33μMTarget: oxytocin receptor

Name	OT-R antagonist 2
Synonyms	(4E)-N-[(2S)-2-Hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl-4-biphenylyl)carbonyl]-L-prolinamide 2-Pyrrolidinecarboxamide, N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino)-1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-, (2S,4E)-

Description	OT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).IC50 value: 0.33μMTarget: oxytocin receptor
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor Research Areas >> Others
References	[1]. Cirillo R, et al. Pharmacology of (2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a new potent and selective nonpeptide antagonist of the oxytocin receptor. J Pharmacol Exp T [2]. William Nadler, et al. Method for preparing pyrrolidine oximes. WO/2005082848/A2. [3]. Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors.WO/2001074769/A1. [4]. Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors. WO/2001072705/A1.