Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CMI977
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Mln-977
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

175212-04-1

175212-04-1 structure

175212-04-1 structure

Name: CMI977
Chemical Name: CMI977
CAS Number: 175212-04-1
Molecular Formula: C₁₆H₁₉FN₂O₄
Molecular Weight: 322.33
Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
Create Date: 2018-03-15 20:32:46
Modify Date: 2025-08-25 13:14:52
CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.

Name	CMI977
Synonyms	Urea, N-hydroxy-N-propyl- Q5WMS52P89 VNR0T3Q498 1-Hydroxy-1-propylurea

Description	CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase Research Areas >> Inflammation/Immunology
In Vitro	CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development.
References	[1]. Xiong Cai, et al. Synthesis of CMI-977, a Potent 5-Lipoxygenase Inhibitor. Org. Proc. Res. Dev., 1999, 3 (1), pp 73-76.

Density	1.2±0.1 g/cm3
Boiling Point	233.6±23.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₉FN₂O₄
Molecular Weight	322.33
Flash Point	95.0±22.6 °C
LogP	0.52
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.499
Storage condition	2-8℃

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