175212-04-1
175212-04-1 structure
- Name: CMI977
- Chemical Name: CMI977
- CAS Number: 175212-04-1
- Molecular Formula: C16H19FN2O4
- Molecular Weight: 322.33
- Catalog: Signaling Pathways Metabolic Enzyme/Protease 5-Lipoxygenase
- Create Date: 2018-03-15 20:32:46
- Modify Date: 2024-01-13 21:11:54
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CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.
| Name | CMI977 |
|---|---|
| Synonyms |
Urea, N-hydroxy-N-propyl-
Q5WMS52P89 VNR0T3Q498 1-Hydroxy-1-propylurea |
| Description | CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor. |
|---|---|
| Related Catalog | |
| In Vitro | CMI977 is a potent 5-lipoxygenase (5-LO) inhibitor that intervenes in the production of leukotrienes and is presently being developed for the treatment of chronic asthma. It is a single enantiomer with an all-trans (2S,5S) configuration. Of the four isomers of CMI977, the S,S isomer is found to have the best biological activity and is selected for further development. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 233.6±23.0 °C at 760 mmHg |
| Molecular Formula | C16H19FN2O4 |
| Molecular Weight | 322.33 |
| Flash Point | 95.0±22.6 °C |
| LogP | 0.52 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.499 |
| Storage condition | 2-8℃ |