1515855-97-6

1515855-97-6 structure

Name: JJKK 048
Chemical Name: JJKK 048
CAS Number: 1515855-97-6
Molecular Formula: C₂₃H₂₂N₄O₅
Molecular Weight: 434.445
Catalog: Signaling Pathways Metabolic Enzyme/Protease MAGL
Create Date: 2018-04-26 00:40:58
Modify Date: 2025-08-26 11:49:07
JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase (MAGL).

Name	JJKK 048
Synonyms	{4-[Bis(1,3-benzodioxol-5-yl)methyl]-1-piperidinyl}(1H-1,2,4-triazol-1-yl)methanone Methanone, [4-[bis(1,3-benzodioxol-5-yl)methyl]-1-piperidinyl]-1H-1,2,4-triazol-1-yl-

Description	JJKK 048 is an ultrapotent and highly selective inhibitor of Monoacylglycerol lipase (MAGL).
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> MAGL Research Areas >> Neurological Disease
Target	MAGL[1]
References	[1]. Aaltonen N, et al. In Vivo Characterization of the Ultrapotent Monoacylglycerol Lipase Inhibitor {4-[bis-(benzo[d][1,3]dioxol-5-yl)methyl]-piperidin-1-yl}(1H-1,2,4-triazol-1-yl)methanone (JJKK-048). J Pharmacol Exp Ther. 2016 Oct;359(1):62-72. [2]. Aaltonen N, et al. Piperazine and piperidine triazole ureas as ultrapotent and highly selective inhibitors of monoacylglycerol lipase. Chem Biol. 2013 Mar 21;20(3):379-90.